Experimental study on seismic performance of novel precast concrete...
AbstractTo improve the reliability and construction efficiency of precast reinforced concrete frame structures, novel precast beam-column joints using mechanical connections were proposed in this...
View ArticleEfficacy and safety of geptanolimab (GB226) for relapsed/refractory primary...
AbstractBackgroundThis study aimed to assess the efficacy and safety of geptanolimab (GB226), a fully humanized, recombinant anti-programmed cell death-1 monoclonal antibody, in Chinese patients with...
View ArticleRisk factors of early mortality in patients with small cell lung cancer: a...
AbstractBackgroundSmall cell lung cancer (SCLC) is a highly aggressive neuroendocrine cancer with a high risk of early mortality (i.e., survival time less than 1 month). This study aimed to identify...
View ArticleAssociations between polygenic risk score and covid-19 susceptibility and...
AbstractBackgroundCOVID-19 manifests with huge heterogeneity in susceptibility and severity outcomes. UK Black Asian and Minority Ethnic (BAME) groups have demonstrated disproportionate burdens. Some...
View ArticleEnhanced anisotropic radius basis function metamodel based on recursive...
AbstractMetamodels are popular approaches to improve design efficiency in practical-engineering problems through replacing the time-consuming simulation models with easy-to-evaluate numerical models....
View ArticleTime-reversal invariance violation and quantum chaos induced by magnetization...
AbstractWe investigate the fluctuation properties in the eigenfrequency spectra of flat cylindrical microwave cavities that are homogeneously filled with magnetized ferrite. These studies are motivated...
View ArticleComorbidities associated with the severity of COVID-19, and differences...
AbstractBackgroundDisparities in COVID-19 outcomes exist on the basis of ethnicity and comorbidities. Minority ethnic groups in the UK are known to have poorer COVID-19 outcomes, but also an increased...
View ArticleCan direct finance within a servitizing supply chain reduce the moral hazard...
AbstractServitizing business models can provide economic benefits in a supply chain by utilizing products more efficiently. However, the transfer of the burden to keep the product operable from the...
View ArticleAmelioration Effect of Biochar on Nitrogen Transformation and Secondary...
AbstractThe cultivation of vegetables within controlled environments is concomitant with the challenges of soil secondary salinization and diminishing soil fertility, rendering continuous cultivation a...
View ArticleGenome-wide analysis revealed the dysregulation of RNA binding...
AbstractBackgroundMyocardial ischemia reperfusion injury (MIRI), the tissue damage which is caused by the returning of blood supply to tissue after a period of ischemia, greatly reduces the therapeutic...
View ArticleClik here to view.
Exogenous H2S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1...
AbstractExcessive ROS accumulation contributes to cardiac injury in type 2 diabetes mellitus. Hydrogen sulfide (H2S) is a vital endogenous gasotransmitter to alleviate cardiac damage in diabetic...
View ArticleOptimization on Aerodynamic Performances of Pantograph Combined with Sample...
AbstractThe increase in the running speed aggravated the influence of the pantograph aerodynamic uplift force on the pantograph-catenary contact force. Moreover, the longitudinal asymmetry of the...
View ArticleGenetic insights into resting heart rate and its role in cardiovascular disease
AbstractResting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting...
View ArticleCOVID-19 in Systemic Lupus Erythematosus patients treated with belimumab: a...
AbstractBackgroundRoutine use of immunosuppressive agents in systemic lupus erythematosus (SLE) patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) potentially increases...
View ArticleVibration Characteristics of High-Speed Train Axle Box Bearing with Raceway...
AbstractAxle box bearing (ABB) of a high-speed train transmits the loads and motions between the wheelset and bogie, which is essential to the operation. The ABBs may experience raceway defects during...
View ArticleA Context-Encoders-Based Generative Adversarial Networks for Cine Magnetic...
AbstractCine imaging serves as a vital approach for non-invasive assessment of cardiac functional parameters. The imaging process of Cine cardiac MRI is inherently slow, necessitating the acquisition...
View ArticleGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
AbstractType 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to...
View ArticleA novel ferroptosis-related gene signature for overall survival prediction in...
AbstractThe global diagnosis rate and mortality of gastric cancer (GC) are among the highest. Ferroptosis and iron-metabolism have a profound impact on tumor development and are closely linked to...
View ArticleGenome-wide characterization of circulating metabolic biomarkers
AbstractGenome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1–7. This detailed knowledge of the genetic...
View ArticleEffects of Different Volumes of Ropivacaine for Pericapsular Nerve Group...
AbstractIntroductionThe pericapsular nerve group (PENG) block has been shown to be an effective approach to alleviating pain and reducing the need for opioids among older adults following hip surgery,...
View Article